NANOLITER LIQUID HANDLING

96 or 384 FIXED TRANSFER, 25nl-1000nl DRUG DISCOVERY

Drug discovery can be approached in a variety of ways. Screening a large number of compounds using defined biochemical assays in an ultra high- throughput format process. However, the effect of a drug on an organism is complex and involves interactions at multiple levels that cannot be predicted using biochemical assays. In order to understand this complexity, an increased use of cell-based screening assays as more biologically relevant surrogates to predict the response of the organism. In addition, at some point in the drug discovery process, predicting cellular toxicity is important. Eukaryotic cell culture is accepted as the model system of choice to get a first approximation of toxicity.

Cellular Life Sciences provides various instrument and tools relate to cell based assays, such as high-throughput cell culture, low volume cell dispensing, etc.

LIBRARY MANAGEMENT

Some of the many reasons to automate assay assembly are to standardize processes, reduce technician time and reduce assay volume. Reducing assay volumes is a popular trend as it reduces costs and can be accomplished by using low volume, high density plates with 384 or 1536 well formats. Automation using fast, non-contact ‘on the fly’ dispensing delivers reagents accurately and precisely into the wells in the volume range of 20nl and greater with CV’s of less than 10%. Multiple reagents can be dispensed while controlling the order and amount, additionally fluidic inertia ensures efficient mixing of the reagents. Virtually anything can be dispensed, examples include alcohol, PEG, cells, SDS, protein solutions and more. Common applications include sequencing, ELISAs, SPA bead and cytotoxicity assays, Genotyping, and other PCR based Assays. Please review our product information on MicroSys.

Cellular Life Sciences offers its patented synQUAD™ Technology in a wide range of instrument configurations to meet your automated assay assembly requirements. Please see the synQUAD system details to find the platform that fits your format and throughput needs.

1-17 DISPENSERS, 20nl-250ul ASSAY ASSEMBLY

Some of the many reasons to automate assay assembly are to standardize processes, reduce technician time and reduce assay volume. Reducing assay volumes is a popular trend as it reduces costs and can be accomplished by using low volume, high density plates with 384 or 1536 well formats. Automation using fast, non-contact ‘on the fly’ dispensing delivers reagents accurately and precisely into the wells in the volume range of 20nl and greater with CV’s of less than 10%. Multiple reagents can be dispensed while controlling the order and amount, additionally fluidic inertia ensures efficient mixing of the reagents. Virtually anything can be dispensed, examples include alcohol, PEG, cells, SDS, protein solutions and more. Common applications include sequencing, ELISAs, SPA bead and cytotoxicity assays, Genotyping, and other PCR based Assays. Please review our product information on MicroSys.

Cellular Life Sciences offers its patented synQUAD™ Technology in a wide range of instrument configurations to meet your automated assay assembly requirements. Please see the synQUAD™ system details to find the platform that fits your format and throughput needs.

PROTEIN CRYSTALLIZATION (SITTING DROP / HANGING BATCH / MICRO BATCH)

The protein crystallization process involves long wait periods of weeks or months during which the actual protein crystals are formed under controlled conditions. It is highly desirable to test more than one condition at a time to get to results faster and to use only small amounts of proteins. Robotic nanoliter dispensing instrumentation can be used to rapidly set up large numbers of protein crystallization conditions.

Sphere Fluidics
Media Analytika
insion
Miacom
solvdinc.com